Biotin-PEG-CHO，生物素PEG醛基

Biotin-PEG-CHO，生物素PEG醛基  

基本信息：

中文名称：生物素聚乙二醇醛基  Biotin-PEG-CHO

中文别名：生物素PEG醛基  

英文名称：Biotin-PEG-aldehyde，Biotin-PEG-CHO

CAS：-

分子量： 400、600、1K、2K、3.4K、5K、10K、20K

纯度：95%以上

应用简介：

 Biotin-PEG-CHO

Biotin functionalized polyethylene glycol(PEG-Biotin) is an avidin or

streptavidin binding PEG derivative thatis used to biotinylate biomolecules or other material surfaces. Biotin can beeasily detected by biotin/streptavidin binding assay and is widely used formolecule target detection.

AldeydePEG is an amine reactive PEG derivative that can be used to modify biomoleculesvia available amine groups. The reaction between aldehyde group with ε-amine oflysine residues and the α-amine at the N-terminus produces an intermediateSchiff base. Further reduction with hydride will form a stable C-N bond. PEGaldehydes react with amine groups at a pH of from 5.5 to 9.5. Higher pH willresult in multiple Pegylation with both terminal and lysine groups. AldehydePEG is a commonly used PEG reagent for n-terminus pegylation in proteins orpeptides.

物理性质：

状态：液体或者固体。

溶解性：溶于DMSO,DMF,DCM，溶于水。

保持条件：-20℃长期保存，避光，干燥。

注意事项：取用一定要干燥，避免频繁的溶解和冻干。

技术指标：

纯度（PEG）：95%以上

取代率（Biotin）：90%以上

取代率（CHO）：90%以上

分散系数（PDI）：小于等于1.05

分析：COA、GPC、NMR、MALDI-TOF