• 【3D 图像分割】基于 Pytorch 的 VNet 3D 图像分割6(数据预处理)


    由于之前哔站作者整理的LUNA16数据处理方式过于的繁琐,于是,本文就对LUNA16数据做一个新的整理,最终得到的数据和形式是差不多的。但是,主要不同的是代码逻辑比较的简单,便于理解。

    对于LUNA16数据集的学习,可以去参考这里:【3D 图像分类】基于 Pytorch 的 3D 立体图像分类3(LIDC-IDRI 肺结节 XML 特征标签 PKL 转储)

    本文的主要步骤和中心内容,包括一下几个部分:

    1. masks生成:从xml文件中,抽取出对应序列series的结节标记位置坐标(可能一个结节多人多次标注),生成对应的mask数组文件,大小与图像数组大小一致;
    2. 肺实质提取操作:从肺区分割的数据中,与原始图像和mask图做乘积操作,非肺区部分进行填充,或者去除操作均可;
    3. resample操作:根据spacing,进行resample操作,可以在zyx三个维度进行resample,也可以仅仅在z方向进行resample操作位1mm(这个我在论文中看到有类似这样做的);
    4. 根据mask,获取结节的zyx中心点坐标,和半径。

    至此,我们将收获以下几个文件:

    1. 包含ct的图像数据;
    2. 对应的mask数据;
    3. 记录zyx中心点坐标,和半径的文件。

    相比于luna16给出的数据形式,目前的数据就比较好理解,和方便查看了。无论是可视化,还是后续的数据处理和训练,都更加的直观、明了。后面就会针对这部分,一一进行展开。

    由于代码量还是比较大,处理的东西,和涉及的文件比较多,可能会几个篇章展开。本篇就先对xml文件进行处理,转出来,以便于查看。这里涉及到xml文件的格式,和处理,就单独开一篇,链接去参考:【医学影像数据处理】 XML 文件格式处理汇总

    一、xml文件转储

    1.1、认识标注文件xml

    对于LIDC-IDRI数据集中,xml文件内各个字段表示什么意思的介绍,可以参考我的另一篇文章,点击这里:【LIDC-IDRI】 CT 肺结节 XML 标记特征良恶性标签PKL转储(一)

    1

    在这篇文章里面,着重介绍了这个数据的结构,以及xml各个记录的tag是什么意思。相信你看完,对这个数据集的处理,有更深的理解。

    其中大部分代码都是跟上面这个链接介绍和获取的内容是一样的,可以参考这个GitHub:NoduleNet - utils -LIDC

    有些内容没有介绍到,简单做个补充

    • ResponseHeader:这个是头部分,记录了这个病例(也就是单个病人的CT图像)的信息。

    为了方便查看,和学习xml文件,可以参考这篇文章:【医学影像数据处理】 XML 文件格式处理汇总。我们就采用其中xml转字典的形式,方便我们查看。下面就展示了转字典后的前后部分内容对比,如下:

    原始xml的数据形式,节选了其中的一小段,展示如下:

    
    <LidcReadMessage uid="1.3.6.1.4.1.14519.5.2.1.6279.6001.1308168927505.0" xmlns="http://www.nih.gov" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.nih.gov http://troll.rad.med.umich.edu/lidc/LidcReadMessage.xsd">
      <ResponseHeader>
        <Version>1.7Version>
        <MessageId>1148851MessageId>
        <DateRequest>2005-11-03DateRequest>
        <TimeRequest>12:25:10TimeRequest>
        <RequestingSite>removedRequestingSite>
        <ServicingSite>removedServicingSite>
        <TaskDescription>Second unblinded readTaskDescription>
        <CtImageFile>removedCtImageFile>
        <SeriesInstanceUid>1.3.6.1.4.1.14519.5.2.1.6279.6001.131939324905446238286154504249SeriesInstanceUid>
        <StudyInstanceUID>1.3.6.1.4.1.14519.5.2.1.6279.6001.303241414168367763244410429787StudyInstanceUID>
        <DateService>2005-11-03DateService>
        <TimeService>12:25:40TimeService>
        <ResponseDescription>1 - Reading completeResponseDescription>
        <ResponseComments>ResponseComments>
      ResponseHeader>
    
    • 1
    • 2
    • 3
    • 4
    • 5
    • 6
    • 7
    • 8
    • 9
    • 10
    • 11
    • 12
    • 13
    • 14
    • 15
    • 16
    • 17
    • 18

    转换成dictionary字典后的形式。(更便于查看了)

    {
      "LidcReadMessage": {
        "@uid": "1.3.6.1.4.1.14519.5.2.1.6279.6001.1308168927505.0",
        "@xmlns": "http://www.nih.gov",
        "@xmlns:xsi": "http://www.w3.org/2001/XMLSchema-instance",
        "@xsi:schemaLocation": "http://www.nih.gov http://troll.rad.med.umich.edu/lidc/LidcReadMessage.xsd",
        "ResponseHeader": {
          "Version": "1.7",
          "MessageId": "1148851",
          "DateRequest": "2005-11-03",
          "TimeRequest": "12:25:10",
          "RequestingSite": "removed",
          "ServicingSite": "removed",
          "TaskDescription": "Second unblinded read",
          "CtImageFile": "removed",
          "SeriesInstanceUid": "1.3.6.1.4.1.14519.5.2.1.6279.6001.131939324905446238286154504249",
          "StudyInstanceUID": "1.3.6.1.4.1.14519.5.2.1.6279.6001.303241414168367763244410429787",
          "DateService": "2005-11-03",
          "TimeService": "12:25:40",
          "ResponseDescription": "1 - Reading complete",
          "ResponseComments": null
        },
    }
    
    • 1
    • 2
    • 3
    • 4
    • 5
    • 6
    • 7
    • 8
    • 9
    • 10
    • 11
    • 12
    • 13
    • 14
    • 15
    • 16
    • 17
    • 18
    • 19
    • 20
    • 21
    • 22
    • 23

    1.2、xml综合记录转为按series的npy文件

    LIDC-IDRI1018个检查,在标记文件夹tcia-lidc-xml6 个文件夹中,有1318 xml文件。并且,这些xml文件的名称,和图像的序列名称不是一一对应的。

    所以,就需要现将xml文件内标注的信息,给重新整理出来,转为人能轻易看懂和理解的内容。并且,标注文件如果能与图像文件是一一对应的,那么后续的处理也会方便了许多。

    这一小节做的事情,就是将xml文件,给抽取出来,留下关心的内容,其他不重要的,不关心的内容暂时不管。

    下面是处理的代码,主要的步骤如下概述:

    1. 遍历所有的xml文件,一一处理;
    2. 对单个xml文件,解析出seriesuid和标注的结节坐标;
    3. 存储到以seriesuid命名的npy文件,存储的内容就是一个个结节坐标。

    完整代码如下:

    from tqdm import tqdm
    import sys
    import os
    import numpy as np
    
    from pylung.utils import find_all_files
    from pylung.annotation import parse
    
    def xml2mask(xml_file):
        header, annos = parse(xml_file)  # get one xml info
    
        ctr_arrs = []
        for i, reader in enumerate(annos):
            for j, nodule in enumerate(reader.nodules):
                ctr_arr = []
                for k, roi in enumerate(nodule.rois):
                    z = roi.z
                    for roi_xy in roi.roi_xy:
                        ctr_arr.append([z, roi_xy[1], roi_xy[0]])  # [[[z, y, x], [z, y, x]]]
                ctr_arrs.append(ctr_arr)
    
        seriesuid = header.series_instance_uid
        return seriesuid, ctr_arrs
    
    def annotation2masks(annos_dir, save_dir):
        # get all xml file path
        files = find_all_files(annos_dir, '.xml')
        for f in tqdm(files, total=len(files)):
            print(f)
            try:
                seriesuid, masks = xml2mask(f)
                np.save(os.path.join(save_dir, '%s' % (seriesuid)), masks)  # save xml 3D coor [[z, y, x], [z, y, x]]
            except:
                print("Unexpected error:", sys.exc_info()[0])
    
    
    if __name__ == '__main__':
        annos_dir = './LUNA16/annotation/LIDC-XML-only/tcia-lidc-xml'     # .xml
        ctr_arr_save_dir = './LUNA16/annotation/noduleCoor'  # 保存每个注释器解析的中间结节mask的地方
    
        os.makedirs(ctr_arr_save_dir, exist_ok=True)
    
        # xml信息,转储npy(临时文件)
        annotation2masks(annos_dir, ctr_arr_save_dir)
    
    • 1
    • 2
    • 3
    • 4
    • 5
    • 6
    • 7
    • 8
    • 9
    • 10
    • 11
    • 12
    • 13
    • 14
    • 15
    • 16
    • 17
    • 18
    • 19
    • 20
    • 21
    • 22
    • 23
    • 24
    • 25
    • 26
    • 27
    • 28
    • 29
    • 30
    • 31
    • 32
    • 33
    • 34
    • 35
    • 36
    • 37
    • 38
    • 39
    • 40
    • 41
    • 42
    • 43
    • 44

    下面打开一个·npy·文件进行查看,记录的内容如下,是所有医生对这个序列标注的所有结节的polygon坐标点:

    [list([[-299.8, 206, 42], [-299.8, 207, 41], [-299.8, 208, 41], [-299.8, 209, 40], [-299.8, 210, 40], [-299.8, 211, 41], [-299.8, 212, 41], [-299.8, 213, 42], [-299.8, 214, 42], [-299.8, 215, 43], [-299.8, 216, 44], [-299.8, 216, 45], [-299.8, 215, 46], [-299.8, 215, 47], [-299.8, 215, 48], [-299.8, 214, 49], [-299.8, 213, 49], [-299.8, 212, 49], [-299.8, 211, 49], [-299.8, 210, 49], [-299.8, 209, 49], [-299.8, 208, 48], [-299.8, 207, 47], [-299.8, 207, 46], [-299.8, 206, 45], [-299.8, 206, 44], [-299.8, 206, 43], [-299.8, 206, 42], [-298.0, 206, 46], [-298.0, 207, 45], [-298.0, 207, 44], [-298.0, 208, 43], [-298.0, 209, 42], [-298.0, 209, 41], [-298.0, 210, 40], [-298.0, 211, 40], [-298.0, 212, 39], [-298.0, 213, 40], [-298.0, 214, 41], [-298.0, 215, 42], [-298.0, 215, 43], [-298.0, 216, 44], [-298.0, 216, 45], [-298.0, 216, 46], [-298.0, 216, 47], [-298.0, 215, 48], [-298.0, 214, 48], [-298.0, 213, 48], [-298.0, 212, 48], [-298.0, 211, 48], [-298.0, 210, 48], [-298.0, 209, 48], [-298.0, 208, 48], [-298.0, 207, 47], [-298.0, 206, 46], [-296.2, 209, 42], [-296.2, 210, 41], [-296.2, 211, 40], [-296.2, 212, 40], [-296.2, 213, 41], [-296.2, 214, 42], [-296.2, 215, 43], [-296.2, 216, 44], [-296.2, 216, 45], [-296.2, 216, 46], [-296.2, 216, 47], [-296.2, 216, 48], [-296.2, 215, 49], [-296.2, 214, 49], [-296.2, 213, 49], [-296.2, 212, 49], [-296.2, 211, 48], [-296.2, 210, 47], [-296.2, 209, 46], [-296.2, 209, 45], [-296.2, 209, 44], [-296.2, 209, 43], [-296.2, 209, 42]])
     list([[-227.8, 151, 405], [-227.8, 152, 404], [-227.8, 153, 403], [-227.8, 154, 402], [-227.8, 155, 402], [-227.8, 156, 402], [-227.8, 157, 403], [-227.8, 157, 404], [-227.8, 157, 405], [-227.8, 158, 406], [-227.8, 158, 407], [-227.8, 158, 408], [-227.8, 157, 409], [-227.8, 156, 409], [-227.8, 155, 409], [-227.8, 154, 408], [-227.8, 153, 408], [-227.8, 152, 407], [-227.8, 151, 406], [-227.8, 151, 405], [-226.0, 152, 405], [-226.0, 153, 404], [-226.0, 154, 404], [-226.0, 155, 403], [-226.0, 156, 404], [-226.0, 157, 405], [-226.0, 157, 406], [-226.0, 157, 407], [-226.0, 156, 408], [-226.0, 155, 408], [-226.0, 154, 408], [-226.0, 153, 408], [-226.0, 152, 407], [-226.0, 152, 406], [-226.0, 152, 405]])
     list([[-226.0, 158, 407], [-226.0, 157, 408], [-226.0, 156, 409], [-226.0, 155, 409], [-226.0, 154, 409], [-226.0, 153, 409], [-226.0, 152, 408], [-226.0, 151, 407], [-226.0, 152, 406], [-226.0, 153, 405], [-226.0, 153, 404], [-226.0, 154, 403], [-226.0, 155, 402], [-226.0, 156, 402], [-226.0, 157, 403], [-226.0, 158, 404], [-226.0, 158, 405], [-226.0, 158, 406], [-226.0, 158, 407], [-227.8, 159, 407], [-227.8, 158, 408], [-227.8, 157, 409], [-227.8, 156, 410], [-227.8, 155, 410], [-227.8, 154, 410], [-227.8, 153, 409], [-227.8, 152, 408], [-227.8, 151, 407], [-227.8, 151, 406], [-227.8, 151, 405], [-227.8, 152, 404], [-227.8, 153, 403], [-227.8, 154, 402], [-227.8, 155, 402], [-227.8, 156, 402], [-227.8, 157, 403], [-227.8, 158, 404], [-227.8, 158, 405], [-227.8, 158, 406], [-227.8, 159, 407]])
     list([[-296.2, 214, 46], [-296.2, 213, 47], [-296.2, 212, 47], [-296.2, 211, 47], [-296.2, 210, 46], [-296.2, 209, 45], [-296.2, 208, 44], [-296.2, 208, 43], [-296.2, 208, 42], [-296.2, 209, 41], [-296.2, 210, 42], [-296.2, 211, 42], [-296.2, 212, 43], [-296.2, 213, 44], [-296.2, 214, 45], [-296.2, 214, 46], [-298.0, 216, 47], [-298.0, 215, 48], [-298.0, 214, 49], [-298.0, 213, 49], [-298.0, 212, 49], [-298.0, 211, 49], [-298.0, 210, 49], [-298.0, 209, 48], [-298.0, 208, 47], [-298.0, 207, 46], [-298.0, 207, 45], [-298.0, 207, 44], [-298.0, 208, 43], [-298.0, 208, 42], [-298.0, 209, 41], [-298.0, 210, 41], [-298.0, 211, 41], [-298.0, 212, 41], [-298.0, 213, 41], [-298.0, 214, 42], [-298.0, 215, 43], [-298.0, 216, 44], [-298.0, 216, 45], [-298.0, 216, 46], [-298.0, 216, 47], [-299.8, 216, 50], [-299.8, 215, 51], [-299.8, 214, 51], [-299.8, 213, 50], [-299.8, 212, 50], [-299.8, 211, 50], [-299.8, 210, 49], [-299.8, 209, 48], [-299.8, 208, 47], [-299.8, 207, 46], [-299.8, 207, 45], [-299.8, 207, 44], [-299.8, 208, 43], [-299.8, 209, 42], [-299.8, 210, 42], [-299.8, 211, 41], [-299.8, 212, 41], [-299.8, 213, 42], [-299.8, 214, 42], [-299.8, 215, 43], [-299.8, 216, 44], [-299.8, 216, 45], [-299.8, 216, 46], [-299.8, 216, 47], [-299.8, 216, 48], [-299.8, 216, 49], [-299.8, 216, 50]])
     list([[-226.0, 158, 407], [-226.0, 157, 408], [-226.0, 156, 409], [-226.0, 155, 409], [-226.0, 154, 409], [-226.0, 153, 409], [-226.0, 152, 409], [-226.0, 151, 409], [-226.0, 151, 408], [-226.0, 151, 407], [-226.0, 151, 406], [-226.0, 151, 405], [-226.0, 152, 404], [-226.0, 152, 403], [-226.0, 153, 403], [-226.0, 154, 402], [-226.0, 154, 401], [-226.0, 155, 401], [-226.0, 156, 401], [-226.0, 157, 401], [-226.0, 157, 402], [-226.0, 158, 403], [-226.0, 158, 404], [-226.0, 158, 405], [-226.0, 158, 406], [-226.0, 158, 407], [-227.8, 159, 407], [-227.8, 158, 408], [-227.8, 158, 409], [-227.8, 157, 409], [-227.8, 156, 410], [-227.8, 155, 410], [-227.8, 154, 409], [-227.8, 153, 409], [-227.8, 152, 409], [-227.8, 151, 408], [-227.8, 151, 407], [-227.8, 151, 406], [-227.8, 151, 405], [-227.8, 151, 404], [-227.8, 152, 403], [-227.8, 152, 402], [-227.8, 153, 401], [-227.8, 154, 401], [-227.8, 155, 401], [-227.8, 156, 401], [-227.8, 157, 401], [-227.8, 158, 402], [-227.8, 158, 403], [-227.8, 159, 404], [-227.8, 159, 405], [-227.8, 159, 406], [-227.8, 159, 407]])
     list([[-296.2, 215, 47], [-296.2, 214, 48], [-296.2, 213, 48], [-296.2, 212, 48], [-296.2, 211, 48], [-296.2, 210, 47], [-296.2, 209, 47], [-296.2, 208, 46], [-296.2, 208, 45], [-296.2, 207, 44], [-296.2, 207, 43], [-296.2, 208, 42], [-296.2, 209, 42], [-296.2, 210, 42], [-296.2, 211, 42], [-296.2, 212, 43], [-296.2, 213, 43], [-296.2, 214, 44], [-296.2, 215, 45], [-296.2, 215, 46], [-296.2, 215, 47], [-298.0, 216, 47], [-298.0, 215, 48], [-298.0, 214, 49], [-298.0, 214, 50], [-298.0, 213, 50], [-298.0, 212, 50], [-298.0, 211, 49], [-298.0, 210, 49], [-298.0, 209, 48], [-298.0, 208, 48], [-298.0, 207, 47], [-298.0, 207, 46], [-298.0, 207, 45], [-298.0, 207, 44], [-298.0, 207, 43], [-298.0, 207, 42], [-298.0, 207, 41], [-298.0, 208, 41], [-298.0, 209, 41], [-298.0, 210, 41], [-298.0, 211, 41], [-298.0, 212, 41], [-298.0, 213, 41], [-298.0, 214, 41], [-298.0, 215, 42], [-298.0, 215, 43], [-298.0, 216, 44], [-298.0, 216, 45], [-298.0, 216, 46], [-298.0, 216, 47], [-299.8, 217, 46], [-299.8, 216, 47], [-299.8, 216, 48], [-299.8, 215, 49], [-299.8, 214, 50], [-299.8, 213, 50], [-299.8, 212, 50], [-299.8, 211, 50], [-299.8, 210, 50], [-299.8, 209, 49], [-299.8, 208, 48], [-299.8, 208, 47], [-299.8, 207, 46], [-299.8, 207, 45], [-299.8, 207, 44], [-299.8, 208, 43], [-299.8, 209, 42], [-299.8, 209, 41], [-299.8, 210, 41], [-299.8, 211, 41], [-299.8, 212, 41], [-299.8, 213, 41], [-299.8, 214, 42], [-299.8, 215, 42], [-299.8, 215, 43], [-299.8, 216, 44], [-299.8, 217, 45], [-299.8, 217, 46], [-301.6, 214, 45], [-301.6, 213, 46], [-301.6, 212, 47], [-301.6, 211, 47], [-301.6, 210, 46], [-301.6, 209, 45], [-301.6, 210, 44], [-301.6, 211, 43], [-301.6, 212, 43], [-301.6, 213, 44], [-301.6, 214, 45]])
     list([[-296.2, 209, 43], [-296.2, 209, 44], [-296.2, 210, 45], [-296.2, 211, 46], [-296.2, 212, 47], [-296.2, 212, 48], [-296.2, 213, 48], [-296.2, 214, 48], [-296.2, 215, 47], [-296.2, 215, 46], [-296.2, 215, 45], [-296.2, 214, 44], [-296.2, 213, 43], [-296.2, 212, 43], [-296.2, 211, 43], [-296.2, 210, 43], [-296.2, 209, 43], [-298.0, 208, 42], [-298.0, 208, 43], [-298.0, 208, 44], [-298.0, 208, 45], [-298.0, 208, 46], [-298.0, 208, 47], [-298.0, 209, 47], [-298.0, 210, 48], [-298.0, 211, 48], [-298.0, 211, 49], [-298.0, 212, 49], [-298.0, 213, 48], [-298.0, 214, 48], [-298.0, 215, 47], [-298.0, 216, 46], [-298.0, 216, 45], [-298.0, 216, 44], [-298.0, 215, 43], [-298.0, 214, 43], [-298.0, 213, 42], [-298.0, 212, 42], [-298.0, 212, 41], [-298.0, 211, 41], [-298.0, 210, 41], [-298.0, 209, 42], [-298.0, 208, 42], [-299.8, 210, 43], [-299.8, 209, 43], [-299.8, 208, 44], [-299.8, 207, 44], [-299.8, 207, 45], [-299.8, 207, 46], [-299.8, 208, 47], [-299.8, 209, 48], [-299.8, 210, 49], [-299.8, 211, 49], [-299.8, 212, 49], [-299.8, 213, 50], [-299.8, 214, 49], [-299.8, 215, 48], [-299.8, 215, 47], [-299.8, 216, 46], [-299.8, 216, 45], [-299.8, 215, 44], [-299.8, 215, 43], [-299.8, 214, 43], [-299.8, 214, 42], [-299.8, 213, 42], [-299.8, 212, 41], [-299.8, 211, 41], [-299.8, 210, 42], [-299.8, 210, 43]])] 
    
    • 1
    • 2
    • 3
    • 4
    • 5
    • 6
    • 7

    二、标记次数和mask数组生成

    生成npy文件并不是此次标注信息的最终结果,有以下几个原因:

    1. xml文件内标注的结节坐标是多个医生分别标注的,所以会存在标注上的重叠(也就是一个结节被多个医生重复标注,很多是背靠背标注,也不知道其他医生标注了什么)。所以需要对多人标注的内容进行处理,留下最终的结节坐标;
    2. 只是坐标点,还需要生成和image一样shape,相互对应的mask文件。

    根据上面几个原因,生成最终mask文件,就需要经历以下几个步骤:

    1. 标记的结节坐标点,需要将hu zinstanceNum处理,对应的图像上;
    2. 对多个医生标注的结节,进行处理,根据iou重叠规则,留下最终的结节;
    3. 留下的结节坐标,绘制到mask上,存储下来。

    实现代码如下:

    import nrrd
    import SimpleITK as sitk
    import cv2
    import os
    import numpy as np
    
    def load_itk_image(filename):
        """
        Return img array and [z,y,x]-ordered origin and spacing
        """
        # sitk.ReadImage返回的image的shape是x、y、z
        itkimage = sitk.ReadImage(filename)
        numpyImage = sitk.GetArrayFromImage(itkimage)
    
        numpyOrigin = np.array(list(reversed(itkimage.GetOrigin())))
        numpySpacing = np.array(list(reversed(itkimage.GetSpacing())))
    
        return numpyImage, numpyOrigin, numpySpacing
    
    
    def arrs2mask(img_dir, ctr_arr_dir, save_dir):
        cnt = 0
        consensus = {1: 0, 2: 0, 3: 0, 4: 0}  # 一致意见
    
        # generate save document
        for k in consensus.keys():
            if not os.path.exists(os.path.join(save_dir, str(k))):
                os.makedirs(os.path.join(save_dir, str(k)))
    
        for f in os.listdir(img_dir):
            if f.endswith('.mhd'):
                pid = f[:-4]
                print('pid:', pid)
                # ct
                img, origin, spacing = load_itk_image(os.path.join(img_dir, '%s.mhd' % (pid)))
    
                # mask coor npy
                ctr_arrs = np.load(os.path.join(ctr_arr_dir, '%s.npy' % (pid)), allow_pickle=True)
                cnt += len(ctr_arrs)
    
                nodule_masks = []
                # 依次标注结节处理
                for ctr_arr in ctr_arrs:
                    z_origin = origin[0]
                    z_spacing = spacing[0]
    
                    ctr_arr = np.array(ctr_arr)
                    # ctr_arr[:, 0] z轴方向值,由hu z到instanceNum  [-50, -40, -30]-->[2, 3, 4]
                    ctr_arr[:, 0] = np.absolute(ctr_arr[:, 0] - z_origin) / z_spacing  # 对数组中的每一个元素求其绝对值。np.abs是这个函数的简写
                    ctr_arr = ctr_arr.astype(np.int32)
                    print(ctr_arr)
    
                    # 每一个标注的结节,都会新临时生成一个与img一样大小的mask文件
                    mask = np.zeros(img.shape)
                    # 遍历标注层的 z 轴序列
                    for z in np.unique(ctr_arr[:, 0]):  # 去除其中重复的元素 ,并按元素 由小到大排序
                        ctr = ctr_arr[ctr_arr[:, 0] == z][:, [2, 1]]
                        ctr = np.array([ctr], dtype=np.int32)
                        mask[z] = cv2.fillPoly(mask[z], ctr, color=(1,))
                    nodule_masks.append(mask)
    
                i = 0
                visited = []
                d = {}
                masks = []
                while i < len(nodule_masks):
                    # If mached before, then no need to create new mask
                    if i in visited:
                        i += 1
                        continue
                    same_nodules = []
                    mask1 = nodule_masks[i]
                    same_nodules.append(mask1)
                    d[i] = {}
                    d[i]['count'] = 1
                    d[i]['iou'] = []
    
                    # Find annotations pointing to the same nodule
                    # 当前结节mask[i],与其后面的所有结节,依次求iou
                    for j in range(i + 1, len(nodule_masks)):
                        # if not overlapped with previous added nodules
                        if j in visited:
                            continue
                        mask2 = nodule_masks[j]
                        iou = float(np.logical_and(mask1, mask2).sum()) / np.logical_or(mask1, mask2).sum()
    
                        # 如果iou超过阈值,则当前第i个mask记为被重复标记一次
                        if iou > 0.4:
                            visited.append(j)
                            same_nodules.append(mask2)
                            d[i]['count'] += 1
                            d[i]['iou'].append(iou)
    
                    masks.append(same_nodules)
                    i += 1
    
                print(visited)
                exit()
                # only 4 people, check up 4 data
                for k, v in d.items():
                    if v['count'] > 4:
                        print('WARNING:  %s: %dth nodule, iou: %s' % (pid, k, str(v['iou'])))
                        v['count'] = 4
                    consensus[v['count']] += 1
    
                # number of consensus
                num = np.array([len(m) for m in masks])
                num[num > 4] = 4  # 最多4次,超过4次重复标记的,记为4次
    
                if len(num) == 0:
                    continue
                # Iterate from the nodules with most consensus
                for n in range(num.max(), 0, -1):
                    mask = np.zeros(img.shape, dtype=np.uint8)
    
                    for i, index in enumerate(np.where(num >= n)[0]):
                        same_nodules = masks[index]
                        m = np.logical_or.reduce(same_nodules)
                        mask[m] = i + 1  # 区分不同的结节,不同的结节给与不同的数值,依次增加(如果是分割,可以直接都给1,或者最后统一处理为1也可以)
                    nrrd.write(os.path.join(save_dir, str(n), pid+'.nrrd'), mask)  # mask
    
        print(consensus)
        print(cnt)
    
    if __name__ == '__main__':
        img_dir = r'./LUNA16/image_combined'        # data
    
        ctr_arr_save_dir = r'./LUNA16/annotation/noduleCoor'  # 保存每个注释器解析的中间结节mask的地方
        noduleMask_save_dir = r'./LUNA16/nodule_masks'  # 保存合并结节掩码的文件夹
    
        # 对转储的临时文件,生成mask
        arrs2mask(img_dir, ctr_arr_save_dir, noduleMask_save_dir)
    
    • 1
    • 2
    • 3
    • 4
    • 5
    • 6
    • 7
    • 8
    • 9
    • 10
    • 11
    • 12
    • 13
    • 14
    • 15
    • 16
    • 17
    • 18
    • 19
    • 20
    • 21
    • 22
    • 23
    • 24
    • 25
    • 26
    • 27
    • 28
    • 29
    • 30
    • 31
    • 32
    • 33
    • 34
    • 35
    • 36
    • 37
    • 38
    • 39
    • 40
    • 41
    • 42
    • 43
    • 44
    • 45
    • 46
    • 47
    • 48
    • 49
    • 50
    • 51
    • 52
    • 53
    • 54
    • 55
    • 56
    • 57
    • 58
    • 59
    • 60
    • 61
    • 62
    • 63
    • 64
    • 65
    • 66
    • 67
    • 68
    • 69
    • 70
    • 71
    • 72
    • 73
    • 74
    • 75
    • 76
    • 77
    • 78
    • 79
    • 80
    • 81
    • 82
    • 83
    • 84
    • 85
    • 86
    • 87
    • 88
    • 89
    • 90
    • 91
    • 92
    • 93
    • 94
    • 95
    • 96
    • 97
    • 98
    • 99
    • 100
    • 101
    • 102
    • 103
    • 104
    • 105
    • 106
    • 107
    • 108
    • 109
    • 110
    • 111
    • 112
    • 113
    • 114
    • 115
    • 116
    • 117
    • 118
    • 119
    • 120
    • 121
    • 122
    • 123
    • 124
    • 125
    • 126
    • 127
    • 128
    • 129
    • 130
    • 131
    • 132

    至此,和image一样shapemask是生成了。下面用itk-snap打开查看处理后的结果,如下所示:

    在这里插入图片描述
    属于分别打开imagemasknrrd图像,mhd格式的image,转nrrd,可以参考下面的代码:

    nii_path = os.path.join(r'./LUNA16/image_combined', '1.3.6.1.4.1.14519.5.2.1.6279.6001.184412674007117333405073397832.mhd')
    image = itk.array_from_image(itk.imread(nii_path))
    
    nrrd.write(r'./image.nrrd', image)
    
    • 1
    • 2
    • 3
    • 4

    三、总结

    lidc-idri的数据集内的数据格式,都是我们不常遇到的数据形式,尤其是mhd文件的raw文件,同时表示一个数据的两个不同部分,也是很少遇到的。

    但是对于初学者来说,理解这种数据形式,还是有些陌生,这部分相信通过本系列可以有较深的理解。与此同时,本篇还存储为nrrd文件,这是我比较喜欢的数组存储格式,理解的好理解和简单。

    到这里,你就收获了一个新的一一对应关系。这样比你看xml文件,理解起来会简单很多。下一节,我们就对初步得到的imagemask,与肺区分割结合,进一步进行精细化处理。resample操作,调整数据到统一的尺度。

  • 相关阅读:
    小黑受到了封校的恐惧,秋招结束该何去何从的日常积累:进程初步
    xdcms漏洞合集-漏洞复现
    unity 射线检测,鼠标点击3D物体交互
    LeetCode简单题之统计星号
    【SwiftUI项目】0009、SwiftUI项目-费用跟踪-记账App项项目-第1/3部分 - 本地数据
    网络编程的对应的四七层结构,以及其对应的协议
    计算机毕业设计Java-ssm阿尔兹海默病源码+系统+数据库+lw文档
    jmap执行失败了,怎么获取heapdump?
    代理模式 工厂模式 原型模式
    清水模板是什么材质?
  • 原文地址:https://blog.csdn.net/wsLJQian/article/details/134071282